The use of amphetamines has distinct regional patterns; past-year use is generally higher among men (0.85 per cent) than women (0.34 per cent) globally.

• The largest markets for ATS, mainly methamphetamine, remain East and South-East Asia and North America. The highest past-year use of amphetamines is recorded in North America, followed by Australia and New Zealand.
• Among amphetamines, methamphetamine use has the widest geographical spread and dominates in North America, Australia and New Zealand, East and South-East Asia, South America and South-West Asia. Treatment data suggest that the geographical spread of this drug is also translating into a growing role in terms of harms.
• Use of amphetamine, on the other hand, dominates in Western and Central Europe.