Methamphetamine-related harms show mixed trends across North America.

• In Mexico, methamphetamine harms have increased in recent years, reflected in a growing number of people entering drug-related treatment for the substance – though recent data suggest possible signs of stabilization.
• In contrast, Canada and the United States of America have shown signs of stabilization at high levels of harm in recent years after earlier increases in methamphetamine-related overdose deaths, treatment admissions and consumption levels (according to wastewater analysis).