List of findings

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Global drug use continues to increase, driven by rising prevalence of use and population growth.An estimated 331 million people used a drug in the past 12 months in 2024, a 34 per cent increase since 2014 (with prevalence of use increasing by 20 per cent).Men account for the majority of users (249…
Cannabis remains the most widely used drug globally, with large differences across substances and regions.With an estimated 256 million users in 2024, cannabis remains by far the most used drug worldwide, followed by the non-medical use of opioids at 63 million.Men have a higher prevalence of drug…
Overall, of the four major modes of transport used for drug trafficking – by land, water, air and mail (including courier services) – land or maritime routes (depending on the specific drug) dominate in terms of volume.Around 2024, there appeared to be an increased preference for smaller shipments…
Opioids and cannabis account for the greatest overall harm globally, though the severity of impacts differs.Combined evidence from country rankings of most harmful drugs and global indicators on deaths, drug use disorders and people in drug-related treatment point to opioids and cannabis resulting…
Globally, the majority of people in drug-related treatment continue to be men, although the proportion of women varies by region, subregion and primary drug.Approximately one in five people in drug-related treatment worldwide is a woman.The lowest proportions of women in drug-related treatment are…
Polydrug use is common among people in drug treatment, with patterns varying by region.According to the limited data available on people in drug treatment, between 40 and 50 per cent of persons in drug-related treatment are polydrug users, with lower levels in Asia (22 per cent) and almost no…
Polydrug use poses significant risks and is more common among people with drug use disorders.No consensus definition of polydrug use currently exists but it can be generally understood as taking two or more drugs together or in sequence (intentionally or unintentionally), with both forms increasing…
The limited data available suggest that most overdose deaths involve multiple substances.Toxicological findings from 22 countries show that a median of 67 per cent of overdose deaths involve more than one substance.In 17 countries with available data, opioids and sedatives/tranquilizers are most…
Cannabis, ATS and opioids account for the highest numbers of people in drug-related treatment globally, with variation between regions and countries.In most reporting countries, cannabis or opioids are the most common primary drug among those in treatment. However, in the Caribbean, South America…
The use of cannabis and stimulant drugs continues to increaseGlobally, the use of cannabis and stimulant drugs such as amphetamines, cocaine and "ecstasy" increased in 2024, while the use of opioids remained largely stable. 
Progress on strengthening the prevention and treatment of substance abuse – as formulated in SDG target 3.5 – remains limited.Coverage of treatment interventions for substance use disorders remains low globally, with new estimates for this indicator suggesting that, at the minimum, 8.2 per cent of…
Socio-economic profiles of people in drug-related treatment vary between regions, although this likely also partly reflects broader regional socio-economic differences.Based on data from 56 countries, employment status varies by region and subregion: in Asia, people in treatment are more likely to…