List of findings

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Men continue to make up the majority of people who use drugs, but gender differences vary by drug and region.In 2024, about three quarters of people who used drugs in the past year were men, though the share of women varies substantially by region and drug type. For example, only 8 per cent of…
Seizures of key pharmaceutical opioids show distinct regional patterns by substance.While fentanyl seizures remain overwhelmingly concentrated in North America (> 99 per cent), other pharmaceutical opioids dominate seizures in different regions: codeine in West and Central Africa and South Asia…
Global opioid use has remained broadly stable, with strong regional differences in prevalence of use.The number of people who use opioids worldwide has remained relatively stable in the last five years, with the estimate for 2024 only slightly higher than the level in 2019.Prevalence of past-year…
Global opiate use has remained broadly stable, with slight declines in the prevalence of use.The number of people using opiates worldwide has remained stable over the last five years, while the annual prevalence of use declined slightly from 0.61 per cent in 2020 to 0.57 per cent in 2023 and 2024.…
Cannabis dominates the global number of seizure cases, followed by ATS (notably methamphetamine) and cocaine while cannabis and cocaine dominate seizures in terms of total weight. 
Drug-related deaths continue to rise globally, with indirect causes accounting for most harm.The total global number of deaths directly or indirectly attributable to drugs continued to increase in 2023, although population-adjusted rates have grown more slowly, suggesting that the growth was in…
Global drug use continues to increase, driven by rising prevalence of use and population growth.An estimated 331 million people used a drug in the past 12 months in 2024, a 34 per cent increase since 2014 (with prevalence of use increasing by 20 per cent).Men account for the majority of users (249…
Cannabis remains the most widely used drug globally, with large differences across substances and regions.With an estimated 256 million users in 2024, cannabis remains by far the most used drug worldwide, followed by the non-medical use of opioids at 63 million.Men have a higher prevalence of drug…
Global illicit opium production remained more than 70 per cent below 2022 levels in 2025Global illicit opium production remained at lower levels in 2025 at 2,100 tons, more than 70 per cent below 2022 (mainly due to Afghanistan’s opium ban) and almost 80 per cent below its 2017 peak.A doubling of…
Myanmar is now the world’s largest opium producer, followed by Afghanistan, Mexico and the Lao People’s Democratic Republic.In Myanmar, opium production continues to be concentrated in the eastern parts of the country, notably in Shan State and in Kachin. This pattern has not changed over the last…
Overall, of the four major modes of transport used for drug trafficking – by land, water, air and mail (including courier services) – land or maritime routes (depending on the specific drug) dominate in terms of volume.Around 2024, there appeared to be an increased preference for smaller shipments…
Seven substances dominate the global availability of opioids under international control for medical consumption.Expressed in S-DDDs (defined daily doses for statistical purposes), methadone, followed by hydrocodone, fentanyl, buprenorphine, oxycodone, codeine (including preparations) and morphine…