Seizures of synthetic NPS have trended upwards since 2018 – though they still remain below the peak reported in 2012.The number of countries reporting seizures of synthetic NPS rose from, on average, just 5 over the period 2000-2004 to 80 over the period 2010-2014, before peaking over the period…
Fentanyls continue to account for the largest share of harm from the non-medical use of NPS synthetic opioids, in particular in North America, but the arrival on the market of nitazenes and orphines , which are often more potent than fentanyls, has led to a number of acute emergencies and fatal…
Limited data suggest stable or declining NPS use among young people, with some exceptions.Time-series data on NPS use among young people are scarce and largely limited to high-income countries.Where data are available, the use of NPS is generally stable or declining, as corroborated by recent…
Globally, the use of synthetic NPS continues to be lower than most internationally controlled drugs.Based on the available data – mainly from high-income countries – the use of synthetic NPS is generally lower than the use of drugs under international control. By contrast, the scarce data on plant-…
