In East and South-East Asia, limited regular data collection makes it difficult to assess long-term trends in opioid use. However, data on people registered for drug use and people in drug treatment indicate a decline in opioid (mainly heroin) use over the past 10 to 15 years.In most of East and…
Opioid-related harms, measured as new people entering treatment, have declined in Europe.Although the share of people in treatment for opioid use disorders remains substantial in Europe, the number of people entering treatment for the first time has decreased.In Eastern Europe and South-Eastern…
The use of buprenorphine and methadone for medical purposes continues to expandMethadone and buprenorphine are the main substances used in substitution treatment for opioid dependent persons worldwide. Availability of both substances for medical use rose 10-fold over the last two decades and…
Opium production and opiate seizures are closely linked, but stockpiling has partly mitigated recent supply shocks.Opiate seizures have generally moved in parallel with opium production over time, but production has been far more volatile. Following the transfer of power in Afghanistan in 2021 and…
Opium prices show diverging trends, reflecting shifting supply dynamics across producing countries.Opium poppy cultivation in Myanmar, increased by 17 per cent in 2025 and more than doubled since 2020, with increases reported across all poppy producing states; this was mirrored by a similar…
Amphetamine seizures rose strongly until 2020-2021, declined thereafter and showed a modest rebound in 2024.Amphetamine seizures remain concentrated in the Near and Middle East (57 per cent of total seizures between 2020 and 2024) and Europe (26 per cent); in the former subregion much of the drug…
The number of NPS on the global market increased strongly in 2024 following a short period of decline between 2021 and 2023.The number of NPS on the global market rose by 30 per cent in 2024 compared to 2023 and reached a new record high of 755 substances – the number rose almost five-fold compared…
Opioids and cannabis account for the greatest overall harm globally, though the severity of impacts differs.Combined evidence from country rankings of most harmful drugs and global indicators on deaths, drug use disorders and people in drug-related treatment point to opioids and cannabis resulting…
Drug offences bring millions into contact with the criminal justice system every year, with outcomes varying by offence type.
In 2024, an estimated 5.9 million people worldwide were in formal contact with the police for criminalized drug offences, with…
Globally, the majority of people in drug-related treatment continue to be men, although the proportion of women varies by region, subregion and primary drug.Approximately one in five people in drug-related treatment worldwide is a woman.The lowest proportions of women in drug-related treatment are…
The global burden of caring with evidence informed interventions for people who inject drugs remains highIn 2024, there were an estimated 14.3 million people who inject drugs, or 0.3 per cent of the population aged 15–64.The highest prevalence of people who inject drugs (PWID) remain in Eastern…
Drug use by injection continues to drive the spread of the HIV epidemic in many countries. The relative risk of acquiring HIV is 14 times higher for those who inject drugs, and even higher for young people and women who inject drugs, than for the general population globally.An estimated 1.7 million…
